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a TUNEL II/III/IV DAPI VI V b Alexa oligo Iba1 c 1.4 1. Merge Igf1 / Gapdh 1 0.8 0.6 0.4 0. * 0 Control sirna IG1 sirna d 1. Igfbp / Gapdh 1 0.8 0.6 0.4 0. ** 0 Control sirna IGBP sirna Supplementary igure 1. The effects of 16,!"#$ sirna, and!"#%&' sirna ()*+(+,. (a) TUNEL positive cells (red, left figure) in layer V of 16 treated cortex at P. DAPI counter staining (blue, right figure) delineates cortical layers (dotted lines). The left figure is the same as igure 6h!"#$%&'"(%)*"+,,"-.!"/b) Alexa labeled control sirna (red) infused in the ventricle and Iba1 staining (green) in the subcortical 01'".%')"/4"1"%6')"7689:7;!"#$%&'"(%)*"+,,"-.!"/c)!-.$ mrna expression in the subcortical white matter of control and IG1 sirna infused group. *& < 0.0 (n = 6, Student s / test). (d)!-.01' mrna expression in the subcortical white matter of control and!"#%&' sirna infused group. **& < 0.01 (n = 4, Student s / test).
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