CasNr: Tester. 96h NOEC 199 Selenastrum capricornutum 2. 48h LC h LC

Transkript

1 Fluroksypyr Fane - Preparat Handelsnavn: Ariane eller Starane Herbicid CasNr: Tester Test-type Test-varighet µg/l Art Litteratur PNEC PNEC Alger akutt Dafnia akutt Dafnia kronisk Fisk akutt Fisk kronisk Vannplanter akutt Vannplanter kronisk 96h EC Selenastrum capricornutum 96h NOEC 99 Selenastrum capricornutum 48h LC d NOEC 00 Daphnia magna 96h LC d NOEC 000 Onchorhynchus 4d EC Lemna gibba 4 4d NOEC 0 Lemna gibba Basert på µg/l Usikkerhetsfaktor Verdi (µg/l) AMF basert på PNEC Laveste L(EC) MF basert på PNEC LavesteNOEC Vurderingsgrunnlag for usikkerhetsfaktor: PNEC: Kronisk NOEC fra tre trofiske nivå. Daphnia mest følsom UF=0 PNEC: L(E)C50 tilgjengelig fra tre trofiske nivå. Alger mest følsom UF=0 Tidligere MFI 43 Fane - Tester Alle tester Test-type Test-varighet µg/l Art Litteratur Vis Alger akutt Alger akutt Dafnia akutt Dafnia kronisk Dafnia kronisk Fisk akutt Fisk kronisk Fisk kronisk Vannplanter akutt Vannplanter kronisk 96h LC h EC Selenastrum capricornutum 0h NOEC h NOEC h NOEC 99 Selenastrum capricornutum 48h LC d NOEC d NOEC 00 Daphnia magna 96h LC d NOEC d NOEC 000 Onchorhynchus 4d EC Lemna gibba 4 4d NOEC 0 Lemna gibba Fane 3 - Kommentarer Fane 4 - r Litteraturreferanser

2 Fluroksypyr European Commission Peer Review Programme. Fluroksypyr Monograph, 996. Rapporteur Member State: Germany Pesticide Ecotoxicity programs, U.S.EPA, Washington, D.C., 00 3 Biologische Bundesanstalt fur Land- und Forstwirtschaft 006, BBA Nr TOMLIN, Ed.: The Pesticide Manual, 006 Fane 5 - Diverse info om preparatet Godkjenelsesdato: Fornyet godkjenning: 006 Trukket (dato): SpesialAnalyse Metode: 6 M5 Bestemmelsesgrense: 0, Dato siste gjennomgang: GC/MS-MULTI Kommentarer

3 Vedlegg for Fluroksypyr Kilde: Svensk undersøkelse 004. Fluroxypyr Fluroxypyr is an auxin type systemic herbicide, intended for use in cereals and pasture. The active moiety is the corresponding acid formed by hydrolysis of the ester. Fluroxypyr has been evaluated within the framework of EU Dir. 9/44. Cl NH Cl -butoxy--methylethyl R = meptyl (-methylheptyl) R = CH 3 (CH ) 3 OCH CH(CH 3 )- CH 3 (CH ) 5 CH(CH 3 )- F N OCH CO R Fluroxypyr ester. Physico-chemical properties Physico-chemical properties of fluroxypyr acid and fluroxypyr-meptyl are summarised in table.. Table.: Physico-chemical properties of fluroxypyr acid and fluroxypyr-meptyl. Fluroxypyr acid Reference Fluroxypyr-meptyl Reference CAS-No Empirical formula C 7 H 5 Cl FN O 3 C 5 H Cl FN O 3 Molecular weight [g/mol] Solubility in water [mg/kg] 5 at ph 3, 0 C 5700 at ph 5.0, 0 C 7300 at ph 9., 0 C at 0 C at ph 5, 0 C at ph 7, 0 C pka.94 Vapour pressure [Pa] Log P ow Henry s law constant [Pa m 3 /mol] Toxicity to aquatic organisms The toxicity of fluroxypyr acid and fluroxypyr-meptyl to aquatic organisms are summarised in table.. Table.: Aquatic ecotoxicity data of fluroxypyr- meptyl. Species End-point Exposure duration Result [mg as/l] Reference Algae Selenastrum 96 h, static EC 50.4 capricornutum NOEC 0.99 ) Scenedesmus growth rate 96 h EC 50 >0.5 subspicatus Higher aquatic

4 plants Lemna gibba 4 d, static EC 50 >.3 NOEC. Crustaceans Palaemonetes 96 h, flow-through EC 50 >0.35 pugio Daphnia magna 48 h, semi-static EC 50 >0. Daphnia magna mortality d, flow through NOEC 0. Fish Lepomis macrochirus mortality 96 h, static-renewal LC 50 >0.63 Cyprionodon mortality 96 h, flow-through LC 50 >0.087 variegatus Oncorhynchus mortality 96 h LC 50 >0 Oncorhynchus mortality 96 h LC 50 >0. Pimephales mortality 96 h LC 50 >0.9 promelas Leuciscus idus mortality 96 h LC 50 >0.7 melanotus Oncorhynchus mortality d, flow-through NOEC.0 ) Effect concentration basis for calculation of PNEC. The most sensitive of the tested species was Selenastrum capricornutum, with a NOEC of 0.99 mg/l (fluroxypyr-meptyl). Since both short and long term studies are available, and three trophic levels have been tested, an assessment factor of 0 is used for calculation of the predicted no effect concentration. Hence, the PNEC for fluroxypyr-meptyl (ester) is calculated to mg/l. The toxicity of fluroxypyr-meptyl to aquatic organisms are summarised in table... Table..: Aquatic ecotoxicity data of fluroxypyr acid. Species End-point Exposure duration Result [mg as/l] Reference Algae Chlorella vulgaris 96 h EC 50 >00 NOEC 56 Higher aquatic plants Lemna gibba 4 d, static EC 50.3 Crustaceans Palaemonetes pugio NOEC < h, flow-through EC 50 >0 Daphnia magna 48 h, static EC 50 >00, Daphnia magna mortality, d, semi-static NOEC 56 reproduction Molluscs Crassostrea virginica 96 h, flow-through EC 50 5 Fish Menidia beryllina mortality 96 h, flow-through LC Oncorhynchus mortality 96 h, static LC 50 >00 Oncorhynchus mortality 96 h LC 50 >00 Lepomis mortality 96 h, static LC ,

5 macrochirus Leuciscus idus melanotus Oncorhynchus mortality 96 h LC 50 >00 mortality d, semi-static NOEC 00 The most sensitive (acute effects) of the tested species was Lemna gibba, with an EC 50 of.3 mg/l and a NOEC of <4.6 mg/l. It is difficult to estimate the chronic toxicity from the long term test. Therefore the PNEC is based on acute toxicity data. Hence, the lowest EC 50 of.3 mg/l is divided by a factor of 00, which results in a PNEC of 0.3 mg/l..3 Bioaccumulation and persistence Fluroxypyr ester has a log P ow of 4.5, indicating potential for bioaccumulation. However the hydrolysation to fluroxypyr acid (with a log P ow of.7) is fast. Hence there is no reason to expect bioaccumulation (). In water fluroxypyr ester adsorb to the sediment but hydrolysis releases fluroxypyr acid in the water. In water/sediment fluroxypyr-meptyl is degraded with a DT 50 of days and fluroxypyr-acid with a DT 50 of 4 d in whole system. Major metabolites are metabolite II and metabolite IV ()..4 Proposed water quality objective Fluroxypyr-meptyl Since PNEC is mg/l, the proposed water quality standard for Fluroxypyr-meptyl is 0.0 mg/l. Fluroxypyr acid Since PNEC is 0.3 mg/l, the proposed water quality standard for fluroxypyr acid is 0. mg/l..5 Comments Fluroxypyr acid is mobile and may reach ground and surface waters via leaching through the soil profile. Metabolite II (4-amino-3,5-dichloro-6-fluoro--pyridinol) shows low toxicity toward algae, daphnia and fish..6 Literature () European Commission Peer Review Programme. Fluroxypyr Monograph, 996. Rapporteur Member State: Germany. () Pesticide Ecotoxicity Database, 00. Environmental Fate and Effects Division of Office of Pesticide programs, U.S.EPA, Washington, D.C.

6